Prdx3 - peroxiredoxin 3 Gene

Also Known as Aop1; Ef2l; Mer5; Prx3; SP22; TDXM; D0Tohi1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11757

Summary

Enables identical protein binding activity. Acts upstream of or within several processes, including maternal placenta development; myeloid cell differentiation; and response to lipopolysaccharide. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and integumental system. Orthologous to human PRDX3 (peroxiredoxin 3). [provided by Alliance of Genome Resources, Apr 2022]

Prdx3 Products (1)

mRNA Protein Name
NM_007452.2 NP_031478.1 thioredoxin-dependent peroxide reductase, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
11591653 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within maternal placenta development IMP
IMP: Inferred from mutant phenotype
18544346 MGI
acts upstream of or within myeloid cell differentiation IMP
IMP: Inferred from mutant phenotype
2210385 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
17316558 MGI
acts upstream of or within response to oxidative stress IMP
IMP: Inferred from mutant phenotype
17316558 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thioredoxin-dependent peroxide reductase, mitochondrial

  • AOP-1

  • Prx III

  • anti-oxidant protein 1

  • mitochondrial Trx dependent peroxide reductase

  • mitochondrial thioredoxin dependent peroxide reductase

  • perioredoxin-3

  • peroxiredoxin III

  • thioredoxin-dependent peroxiredoxin 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P10132 PRDX3(103-112), human / Unkown
HY-P10133 PRDX3(103-112) SO3 modified, human / Unkown
HY-RS11076 PRDX3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17991 Prdx3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24462 Prdx3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prdx3 NCBI NCBI:10935