Smyd1 - SET and MYND domain containing 1 Gene

Also Known as Bop; Zmynd18; 4632404M21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12180

Summary

Enables transcription corepressor activity. Acts upstream of or within several processes, including chromatin remodeling; negative regulation of transcription, DNA-templated; and skeletal muscle cell differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including 1st branchial arch; embryo mesenchyme; heart; maxillary process; and spleen. Orthologous to human SMYD1 (SET and MYND domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Smyd1 Products (2)

mRNA Protein Name
NM_001160127.1 NP_001153599.1 histone-lysine N-methyltransferase Smyd1 isoform 1
NM_009762.2 NP_033892.2 histone-lysine N-methyltransferase Smyd1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11923873 MGI
enables transcription corepressor activity IDA
IDA: Inferred from direct assay
11923873 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within chromatin remodeling IPI
IPI: Inferred from physical interaction
11923873 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
11923873 MGI
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11923873 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
22147266 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11923873 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11923873 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase Smyd1

  • CD8b-opposite

  • CD8beta opposite strand

  • SET and MYND domain-containing protein 1

  • m-BOP

  • zinc finger protein BOP

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13461 SMYD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21759 Smyd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28277 Smyd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smyd1 NCBI NCBI:150572