Cnga2 - cyclic nucleotide gated channel alpha 2 Gene

Also Known as CNG2; Cnca; Cncg4; OCNC1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12789

Summary

This gene encodes a transmembrane protein that is the main subunit of the nucleotide-gated olfactory ion channel, which plays a key role in transducing chemosensory signal resulting from hydrogen sulphide exposure. Signaling pathways mediated by this gene operate in the cilia of type B cells. Knock out of this gene affects development of the olfactory epithelium and olfactory bulb. [provided by RefSeq, Aug 2022]

Cnga2 Products (2)

mRNA Protein Name
NM_001410247.1 NP_001397176.1 cyclic nucleotide-gated olfactory channel
NM_007724.3 NP_031750.2 cyclic nucleotide-gated olfactory channel

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables monoatomic ion channel activity IMP
IMP: Inferred from mutant phenotype
10798394 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within sensory perception of smell IMP
IMP: Inferred from mutant phenotype
10798394 MGI
Cellular Component GO Annotation Evidence References Source
located in ciliary membrane IDA
IDA: Inferred from direct assay
28053034 MGI
located in non-motile cilium membrane IDA
IDA: Inferred from direct assay
16980309 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclic nucleotide-gated olfactory channel

  • CNG channel alpha-2

  • cyclic nucleotide gated channel 4

  • cyclic nucleotide-gated cation channel 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-116540 L 858051 Activator / Unkown
HY-116540A L 858051 dihydrochloride Activator / Unkown
HY-RS02880 CNGA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175080 8-DY547-cGMP / Unkown
HY-RS22448 Cnga2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cnga2 NCBI NCBI:1260