Cnr2 - cannabinoid receptor 2 (macrophage) Gene

Also Known as CB2; CB-2; CB2-R

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12802

About Cnr2

Chromosome 4: 135,622,705-135,647,518 forward strand.GRCm39:CM000997.3

This gene has 2 transcripts (splice variants), 196 orthologues, 18 paralogues and is associated with 18 phenotypes. Biased expression in spleen adult (RPKM 19.7), mammary gland adult (RPKM 6.) and 6 other tissues.

Summary

Predicted to enable Cannabinoid Receptor activity. Acts upstream of or within leukocyte chemotaxis. Predicted to be located in dendrite; endoplasmic reticulum; and neuronal cell body. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and liver and biliary system. Orthologous to human CNR2 (Cannabinoid Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Cnr2 Products (2)

mRNA Protein Name
NM_009924.4 NP_034054.3 cannabinoid receptor 2
NM_001305278.1 NP_001292207.1 cannabinoid receptor 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within leukocyte chemotaxis IDA
IDA: Inferred from direct assay
25348153 MGI
involved in trans-synaptic signaling by endocannabinoid, modulating synaptic transmission EXP
EXP: Inferred from Experiment
27133464 MGI
involved in trans-synaptic signaling by endocannabinoid, modulating synaptic transmission IDA
IDA: Inferred from direct assay
27133464 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Cnr2 Protein Structure

7tmA_CB2

7tmA_CB2: cd15341 (33 - 309)

7tmA_CB2

7tmA_CB2: cd15341 (34 - 60)

7tmA_CB2

7tmA_CB2: cd15341 (68 - 93)

7tmA_CB2

7tmA_CB2: cd15341 (105 - 135)

7tmA_CB2

7tmA_CB2: cd15341 (147 - 167)

7tmA_CB2

7tmA_CB2: cd15341 (185 - 214)

7tmA_CB2

7tmA_CB2: cd15341 (237 - 267)

7tmA_CB2

7tmA_CB2: cd15341 (277 - 302)

  • 0
  • 100
  • 200
  • 300
  • 347 a.a.
Protein Preferred Names Protein Names

cannabinoid receptor 2

  • cannabinoid receptor 2 (spleen)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153169 6PPD-Q Inhibitor 99.77% Unkown
HY-Y1322 Triphenyl phosphate 99.67% Unkown
HY-107713 PPDA Antagonist 98.0% Unkown
HY-RS02917 CNR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02918 Cnr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02919 Cnr2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cnr2 NCBI NCBI:1269