Ctsh - cathepsin H Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13036

Summary

This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the Cathepsin H mini, heavy, and light chains. In rat and human, these three chains can associate to form the mature enzyme, which has both Aminopeptidase and endopeptidase activities. Homozygous knockout mice for this gene exhibit impaired lung surfactant processing and reduced tumorigenesis in a pancreatic Cancer model. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015]

Ctsh Products (2)

mRNA Protein Name
NM_001312649.1 NP_001299578.1 pro-cathepsin H isoform 2
NM_007801.3 NP_031827.2 pro-cathepsin H isoform 1 preproprotein
Protein Preferred Names Protein Names

pro-cathepsin H

  • Cat H

  • cathepsin B3

  • cathepsin BA

Recombinant Ctsh Proteins

Cat. No. Product Name Accession Purity
HY-P7752 Cathepsin H Protein, Mouse (HEK293, His) AAA82966.1 (A21-V333) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS18235 Ctsh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03336 CTSH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24714 Ctsh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctsh NCBI NCBI:1512