OSR1 - odd-skipped related transcription factor 1 Gene

Also Known as ODD

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 130497

About OSR1

Cytogenetic location: 2p24.1 Genomic coordinates (GRCh38): 2:19,344,874-19,358,623 (from NCBI)

This gene has 3 transcripts (splice variants), 205 orthologues and 1 paralogue. Broad expression in salivary gland (RPKM 5.4), endometrium (RPKM 5.3) and 19 other tissues.

Summary

Enables sequence-specific double-stranded DNA binding activity. Involved in negative regulation of ion transmembrane transporter activity; positive regulation of gastrulation; and pronephros development. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

OSR1 Products (1)

mRNA Protein Name
NM_145260.3 NP_660303.1 protein odd-skipped-related 1

OSR1 Protein Structure

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (189 - 213)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (217 - 240)

  • 0
  • 100
  • 200
  • 266 a.a.
Protein Preferred Names Protein Names

protein odd-skipped-related 1

  • odd-skipped homolog

Related Diseases

Diseases Alias
Hydronephrosis

  • Stricture Of Ureteropelvic Junction With Hydronephrosis

  • Hydronephrosis With Ureteral Stricture, Not Elsewhere Classified
Wilms Tumor 1

  • Nephroblastoma

  • Wilms Tumor

  • WT1

  • Wilms' Tumor

  • Bilateral Wilms Tumor

  • Wilms Tumor, Type 1

  • Wilms Tumor, Somatic

  • Adult Nephroblastoma

  • Wt1 Disorder

  • Renal Embryonic Tumor

  • Adult Kidney Wilms Tumor

  • Childhood Kidney Wilms Tumor

  • Nonanaplastic Kidney Wilms Tumor
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-151545 WNK1-IN-1 Inhibitor 98.67% Unkown
HY-175875 HRZ-01-082-5 Degrader / Unkown
HY-E70807 Biotin-WNK3 Recombinant Human Active Protein Kinase / Unkown
HY-RS09852 OSR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09892 OXSR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18147 Osr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19467 Oxsr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24622 Osr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus OSR1 VGNC VGNC:68618
Mus musculus OSR1 MGD MGI:1344424
Bos taurus OSR1 VGNC VGNC:32476
Rattus norvegicus OSR1 RGD RGD:1311807
Canis familiaris OSR1 VGNC VGNC:44168
Others OSR1 NCBI