Dok1 - docking protein 1 Gene

Also Known as p62DOK

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13448

Summary

Acts upstream of or within Ras protein signal transduction; macrophage colony-stimulating factor signaling pathway; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Is expressed in central nervous system and retina. Orthologous to human DOK1 (docking protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Dok1 Products (3)

mRNA Protein Name
NM_001409625.1 NP_001396554.1 docking protein 1 isoform 3
NM_001409626.1 NP_001396555.1 docking protein 1 isoform 4
NM_010070.5 NP_034200.4 docking protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10585470 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Ras protein signal transduction IPI
IPI: Inferred from physical interaction
9008161 MGI
acts upstream of or within cell surface receptor protein tyrosine kinase signaling pathway IPI
IPI: Inferred from physical interaction
10585470 MGI
acts upstream of or within intracellular signal transduction IPI
IPI: Inferred from physical interaction
10585470 MGI
acts upstream of or within macrophage colony-stimulating factor signaling pathway IPI
IPI: Inferred from physical interaction
10585470 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

docking protein 1

  • downstream of tyrosine kinase 1

  • p62(dok)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03933 DOK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01046 ART4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19593 Dok1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19875 Art4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26089 Dok1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dok1 NCBI NCBI:1796