Adam28 - a disintegrin and metallopeptidase domain 28 Gene

Also Known as MDCL; Dtgn1; MDC-L; eMDCII; TECADAM; C130072N01Rik; D430033C21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13522

Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are typically membrane-anchored, although a form of this protein may be secreted. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a mature protein product. This protein may bind to integrins and regulate lymphocyte migration by enhancing cell adhesion. [provided by RefSeq, Aug 2015]

Adam28 Products (3)

mRNA Protein Name
NM_001048175.2 NP_001041640.1 disintegrin and metalloproteinase domain-containing protein 28 isoform 4 precursor
NM_010082.2 NP_034212.1 disintegrin and metalloproteinase domain-containing protein 28 isoform 1 preproprotein
NM_183366.3 NP_899222.1 disintegrin and metalloproteinase domain-containing protein 28 isoform 2 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
15883027 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

disintegrin and metalloproteinase domain-containing protein 28

  • ADAM 28

  • a disintegrin and metalloprotease domain 28

  • a disintegrin and metalloproteinase domain 28

  • disintegrin 1

  • metalloproteinase-disintegrin domain containing protein TECADAM

  • thymic epithelial cell-ADAM

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00280 ADAM28 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19498 Adam28 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25992 Adam28 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adam28 NCBI NCBI:10863