Elf1 - E74 like ETS transcription factor 1 Gene

Also Known as p70; Sts1; Elf-1; mElf-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13709

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of T cell receptor signaling pathway and regulation of cytokine production. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human ELF1 (E74 like ETS transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Elf1 Products (3)

mRNA Protein Name
NM_001286411.1 NP_001273340.1 ETS-related transcription factor Elf-1 isoform 1
NM_001286412.1 NP_001273341.1 ETS-related transcription factor Elf-1 isoform 2
NM_007920.4 NP_031946.1 ETS-related transcription factor Elf-1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
16002702 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
16002702 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
16002702 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within negative regulation of T cell receptor signaling pathway IGI
IGI: Inferred from genetic interaction
14738763 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
16002702 MGI
acts upstream of or within regulation of cytokine production IGI
IGI: Inferred from genetic interaction
14738763 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in nucleus IDA
IDA: Inferred from direct assay
19796622 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ETS-related transcription factor Elf-1

  • E74-like factor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS04193 EFNA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04298 ELF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04320 ELOF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17828 Efna2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19817 Sptbn1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21333 Elf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27852 Elf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Elf1 NCBI NCBI:1997