Elk3 - ELK3, member of ETS oncogene family Gene

Also Known as Erp; Net; Etrp; Sap-2; D430049E23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13713

Summary

Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Acts upstream of or within angiogenesis; regulation of transcription, DNA-templated; and wound healing. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and sensory organ. Used to study congenital chylothorax. Orthologous to human ELK3 (ETS transcription factor ELK3). [provided by Alliance of Genome Resources, Apr 2022]

Elk3 Products (4)

mRNA Protein Name
NM_001282967.1 NP_001269896.1 ETS domain-containing protein Elk-3 isoform Elk3d
NM_001322265.1 NP_001309194.1 ETS domain-containing protein Elk-3 isoform Elk3c
NM_001322268.1 NP_001309197.1 ETS domain-containing protein Elk-3 isoform Elk3b
NM_013508.2 NP_038536.2 ETS domain-containing protein Elk-3 isoform Elk3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
12975317 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
12975317 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within angiogenesis IMP
IMP: Inferred from mutant phenotype
12975317 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12975317 MGI
acts upstream of or within wound healing IMP
IMP: Inferred from mutant phenotype
12975317 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
12975317 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ETS domain-containing protein Elk-3

  • ETS-domain protein ELK-3

  • ETS-related protein ERP

  • ETS-related protein NET

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-107753 XRP44X Inhibitor 98.09% Unkown
HY-RS04306 ELK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07131 KCNH8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21611 Kcnh8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22155 Elk3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28129 Kcnh8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28677 Elk3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Elk3 NCBI NCBI:2004