MAGEC3 - MAGE family member C3 Gene

Also Known as HCA2; CT7.2; MAGEC4; MAGE-C3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 139081

About MAGEC3

Cytogenetic location: Xq27.2 Genomic coordinates (GRCh38): X:141,838,316-141,897,832 (from NCBI)

This gene has 5 transcripts (splice variants), 466 orthologues and 37 paralogues. Low expression observed in reference dataset.

Summary

This gene is a member of the MAGEC gene family. The members of this family are not expressed in normal tissues, except for testis, and are expressed in tumors of various histological types. The MAGEC genes are clustered on chromosome Xq26-q27. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

MAGEC3 Products (2)

mRNA Protein Name
NM_138702.1 NP_619647.1 melanoma-associated antigen C3 isoform 1
NM_177456.2 NP_803251.1 melanoma-associated antigen C3 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MAGEC3 Protein Structure

MAGE

MAGE: MAGE family (191 - 303)

MAGE

MAGE: MAGE family (463 - 576)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 600
  • 643 a.a.
Protein Preferred Names Protein Names

melanoma-associated antigen C3

  • MAGE family testis and tumor-specific protein

Related Diseases

Diseases Alias
Melanoma

  • Malignant Melanoma

  • Cutaneous Melanoma

  • Naevocarcinoma

  • Malignant Melanomas
Adult Hepatocellular Carcinoma

  • Adult Primary Hepatocellular Carcinoma

  • Adult Hepatoma

  • Adult Hcc
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07975 MAGEC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown