CRMP1 - collapsin response mediator protein 1 Gene

Homo sapiens

Also known as DRP1; DRP-1; CRMP-1; DPYSL1; ULIP-3

Gene ID: 1400 | Gene type: protein coding

About CRMP1

Cytogenetic location: 4p16.2 Genomic coordinates (GRCh38): 4:5,820,764-5,893,086 (from NCBI)

This gene has 6 transcripts (splice variants), 195 orthologues and 5 paralogues. Biased expression in brain (RPKM 34.7), endometrium (RPKM 8.3) and 8 other tissues.

Summary

This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

CRMP1 Products(4)

mRNA	Protein	Name
NM_001014809.3	NP_001014809.1	dihydropyrimidinase-related protein 1 isoform 1
NM_001288661.2	NP_001275590.1	dihydropyrimidinase-related protein 1 isoform 3
NM_001288662.1	NP_001275591.1	dihydropyrimidinase-related protein 1 isoform 4
NM_001313.5	NP_001304.1	dihydropyrimidinase-related protein 1 isoform 2

CRMP1 Protein Structure

Amidohydro_1

0
100
200
300
400
500
572 a.a.

Protein Preferred Names

Protein Names

dihydropyrimidinase-related protein 1

dihydropyrimidinase-like 1

Recombinant CRMP1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71547	CRMP1 Protein, Human	Q14194 (M1-G572)	≥95%

Related Diseases

Diseases

Alias

Sialuria

Sialuria, French Type	French Type Sialuria
Sialuria French Type	Sialic Acid Storage Disease
Sialic Acid Storage Disease, Finnish Type	Infantile Sialic Acid Storage Disease

Weyers Acrofacial Dysostosis

Curry-Hall Syndrome	Weyers Acrodental Dysostosis
WAD	Acrodental Dysostosis Of Weyers
Acrofacial Dysostosis, Weyers Type	Acrofacial Dysostosis Of Weyers
Curry Hall Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03190	CRMP1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	CRMP1	VGNC	VGNC:71494
Mus musculus	CRMP1	MGD	MGI:107793
Canis familiaris	CRMP1	VGNC	VGNC:39624
Bos taurus	CRMP1	VGNC	VGNC:27720
Rattus norvegicus	CRMP1	RGD	RGD:2407
Felis catus	CRMP1	VGNC	VGNC:61186
Others	CRMP1	NCBI

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