PAICS - Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase Gene

Also Known as Airc; Ade2h1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 140946

Summary

Predicted to enable identical protein binding activity and phosphoribosylaminoimidazolesuccinocarboxamide synthase activity. Involved in G1/S transition of mitotic cell cycle. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase). [provided by Alliance of Genome Resources, Apr 2022]

PAICS Products (1)

mRNA Protein Name
NM_080910.3 NP_543186.1 bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in G1/S transition of mitotic cell cycle IEP
IEP: Inferred from expression pattern
7742366 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

multifunctional protein ADE2

  • AIR carboxylase-SAICAR synthetase

  • multifunctional protein ADE2-like

  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09980 PAICS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-183046 PAICS-IN-1 Activator / Unkown
HY-RS21010 Paics Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27527 Paics Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PAICS NCBI NCBI:10606