Fbl - fibrillarin Gene

Also Known as FIB; FLRN; RNU3IP1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14113

Summary

Enables RNA binding activity. Acts upstream of or within sno(s)RNA metabolic process. Located in Cajal body and granular component. Is expressed in several structures, including central nervous system; early conceptus; neural retina; oocyte; and submandibular gland primordium. Orthologous to human FBL (fibrillarin). [provided by Alliance of Genome Resources, Apr 2022]

Fbl Products (2)

mRNA Protein Name
NM_001412420.1 NP_001399349.1 rRNA 2'-O-methyltransferase fibrillarin isoform 2
NM_007991.4 NP_032017.2 rRNA 2'-O-methyltransferase fibrillarin isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IPI
IPI: Inferred from physical interaction
24174535 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within sno(s)RNA metabolic process IMP
IMP: Inferred from mutant phenotype
14612397 MGI
Cellular Component GO Annotation Evidence References Source
located in Cajal body IDA
IDA: Inferred from direct assay
7768196 MGI
located in granular component IDA
IDA: Inferred from direct assay
15485902 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
7772340 MGI
located in nucleus IDA
IDA: Inferred from direct assay
32017896 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rRNA 2'-O-methyltransferase fibrillarin

  • U6 snRNA 2'-O-methyltransferase fibrillarin

  • histone-glutamine methyltransferase

  • nucleolar protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N12677 Isocannflavin B 99.9% Unkown
HY-RS04769 FBL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18734 Fbl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25221 Fbl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fbl NCBI NCBI:2091