Fgf17 - fibroblast growth factor 17 Gene

Also Known as Fgf6b; FGF-17

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14171

Summary

Predicted to enable growth factor activity; type 1 Fibroblast Growth Factor receptor binding activity; and type 2 Fibroblast Growth Factor receptor binding activity. Acts upstream of or within Fibroblast Growth Factor receptor signaling pathway and positive regulation of cell population proliferation. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including arterial system; central nervous system; embryo ectoderm; embryo mesenchyme; and skeleton. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 20 with or without anosmia. Orthologous to human FGF17 (Fibroblast Growth Factor 17). [provided by Alliance of Genome Resources, Apr 2022]

Fgf17 Products (2)

mRNA Protein Name
NM_001360108.2 NP_001347037.1 fibroblast growth factor 17 isoform 2 precursor
NM_008004.6 NP_032030.1 fibroblast growth factor 17 isoform 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within fibroblast growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
10381577 MGI
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
10381577 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 17

  • fibroblast growth factor 6b

Recombinant Fgf17 Proteins

Cat. No. Product Name Accession Purity
HY-P72653 FGF-17 Protein, Mouse (His) P63075 (T23-T216) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04893 FGF17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174705 Human FGF17 mRNA / Unkown
HY-RS17701 Fgf17 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24165 Fgf17 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf17 NCBI NCBI:8822