Fhl1 - four and a half LIM domains 1 Gene

Also Known as KyoT; SLIM; FHL-1; SLIM-1; RAM14-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14199

Summary

Predicted to enable transmembrane transporter binding activity. Predicted to be involved in several processes, including negative regulation of mitotic cell cycle phase transition; regulation of membrane depolarization; and regulation of potassium ion transport. Predicted to act upstream of or within cell differentiation. Predicted to be located in cytosol; nucleus; and plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Used to study scapuloperoneal myopathy. Human ortholog(s) of this gene implicated in Uruguay faciocardiomusculoskeletal syndrome; X-linked Emery-Dreifuss muscular dystrophy 6; reducing body myopathy 1A; and reducing body myopathy 1B. Orthologous to human FHL1 (four and a half LIM domains 1). [provided by Alliance of Genome Resources, Apr 2022]

Fhl1 Products (14)

mRNA Protein Name
NM_001077361.2 NP_001070829.1 four and a half LIM domains protein 1 isoform 1
NM_001077362.3 NP_001070830.1 four and a half LIM domains protein 1 isoform 2
NM_001287800.2 NP_001274729.1 four and a half LIM domains protein 1 isoform 3
NM_001412079.1 NP_001399008.1 four and a half LIM domains protein 1 isoform 1
NM_001412080.1 NP_001399009.1 four and a half LIM domains protein 1 isoform 1
NM_001412081.1 NP_001399010.1 four and a half LIM domains protein 1 isoform 1
NM_001412082.1 NP_001399011.1 four and a half LIM domains protein 1 isoform 3
NM_001412083.1 NP_001399012.1 four and a half LIM domains protein 1 isoform 4
NM_001412084.1 NP_001399013.1 four and a half LIM domains protein 1 isoform 5
NM_001412085.1 NP_001399014.1 four and a half LIM domains protein 1 isoform 6
NM_001412086.1 NP_001399015.1 four and a half LIM domains protein 1 isoform 7
NM_001412087.1 NP_001399016.1 four and a half LIM domains protein 1 isoform 7
NM_001412088.1 NP_001399017.1 four and a half LIM domains protein 1 isoform 7
NM_010211.4 NP_034341.2 four and a half LIM domains protein 1 isoform 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24290140 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

four and a half LIM domains protein 1

  • RBP-associated molecule 14-1

  • skeletal muscle LIM-protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02561 CFH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02562 CFHR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04934 FHL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18240 Fhl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24719 Fhl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fhl1 NCBI NCBI:2273