Galk1 - galactokinase 1 Gene

Also Known as Gk; Glk; GALK; Glk1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14635

Summary

Enables Galactokinase activity. Acts upstream of or within galactitol metabolic process and glycolytic process from galactose. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in cataract and Galactokinase deficiency. Orthologous to human GALK1 (Galactokinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Galk1 Products (1)

mRNA Protein Name
NM_016905.2 NP_058601.2 galactokinase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables galactokinase activity IDA
IDA: Inferred from direct assay
186024 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
7519779 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within galactitol metabolic process IMP
IMP: Inferred from mutant phenotype
10915771 MGI
involved in galactose catabolic process via UDP-galactose IMP
IMP: Inferred from mutant phenotype
10915771 MGI
acts upstream of or within galactose metabolic process IDA
IDA: Inferred from direct assay
186024 MGI
acts upstream of or within galactose metabolic process IMP
IMP: Inferred from mutant phenotype
10915771 MGI
acts upstream of or within glycolytic process from galactose IMP
IMP: Inferred from mutant phenotype
10915771 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

galactokinase

  • galactose kinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-128047 GALK1-IN-1 Inhibitor 98.17% Unkown
HY-132888 NCATS-SM4487 / Unkown
HY-113143 Galactose 1-phosphate / Unkown
HY-173642 NCGC00238624 Inhibitor / Unkown
HY-RS05243 GALK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18388 Galk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24869 Galk1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Galk1 NCBI NCBI:2584