Gp1ba - glycoprotein 1b, alpha polypeptide Gene

Also Known as GPIba; GPIbalpha; GP-Ib alpha

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14723

Summary

Acts upstream of or within blood coagulation and cell morphogenesis. Colocalizes with anchored component of external side of plasma membrane. Is expressed in dorsal root ganglion; embryo; liver; and spinal cord. Used to study Bernard-Soulier syndrome. Human ortholog(s) of this gene implicated in Bernard-Soulier syndrome; Bernard-Soulier syndrome type A2; myocardial infarction; non-arteritic anterior ischemic optic neuropathy; and platelet-type bleeding disorder 3. Orthologous to human GP1BA (glycoprotein Ib platelet subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Gp1ba Products (1)

mRNA Protein Name
NM_010326.3 NP_034456.2 platelet glycoprotein Ib alpha chain precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in blood coagulation IDA
IDA: Inferred from direct assay
18187573 MGI
acts upstream of or within blood coagulation IMP
IMP: Inferred from mutant phenotype
20650879 MGI
acts upstream of or within cell morphogenesis IMP
IMP: Inferred from mutant phenotype
10706630 MGI
acts upstream of or within hemostasis IMP
IMP: Inferred from mutant phenotype
10706630 MGI
involved in megakaryocyte development IMP
IMP: Inferred from mutant phenotype
18187573 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
28576878 MGI
colocalizes with external side of plasma membrane IDA
IDA: Inferred from direct assay
19443707 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet glycoprotein Ib alpha chain

  • glycoprotein Ibalpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05607 GP1BA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20029 Gp1ba Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26532 Gp1ba Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gp1ba NCBI NCBI:2811