Gstm3 - glutathione S-transferase, mu 3 Gene

Also Known as Fsc2; mGSTM5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14864

Summary

Predicted to enable several functions, including glutathione binding activity; glutathione transferase activity; and protein homodimerization activity. Acts upstream of or within cellular response to organic cyclic compound; cellular response to xenobiotic stimulus; and response to bacterium. Predicted to be located in cytosol and intercellular bridge. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system Cancer (multiple); hematologic Cancer (multiple); and lung disease (multiple). Orthologous to human GSTM1 (Glutathione S-transferase mu 1). [provided by Alliance of Genome Resources, Apr 2022]

Gstm3 Products (1)

mRNA Protein Name
NM_010359.3 NP_034489.1 glutathione S-transferase Mu 3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to organic cyclic compound IDA
IDA: Inferred from direct assay
6822548 MGI
acts upstream of or within cellular response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
8512323 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutathione S-transferase Mu 3

  • GST class-mu 3

  • glutathione S-transferase GT9.3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-146577 Keap1-Nrf2-IN-7 Inhibitor 99.82% Unkown
HY-146578 Keap1-Nrf2-IN-8 Inhibitor / Unkown
HY-149245 Keap1-Nrf2-IN-15 Inhibitor / Unkown
HY-RS05881 GSTM3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-162096 Keap1-Nrf2-IN-17 Inhibitor / Unkown
HY-RS17764 Gstm3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24231 Gstm3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27466 Gstm5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gstm3 NCBI NCBI:2947