Trip12 - thyroid hormone receptor interactor 12 Gene

Also Known as Gtl6; TRIP-12; 1110036I07Rik; 6720416K24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14897

Summary

Predicted to enable Thyroid Hormone Receptor binding activity and ubiquitin protein Ligase activity. Involved in regulation of embryonic development. Predicted to be located in nucleoplasm. Predicted to be active in nuclear speck. Is expressed in brain and genitourinary system. Human ortholog(s) of this gene implicated in Clark-Baraitser syndrome. Orthologous to human TRIP12 (Thyroid Hormone Receptor interactor 12). [provided by Alliance of Genome Resources, Apr 2022]

Trip12 Products (1)

mRNA Protein Name
NM_133975.4 NP_598736.4 E3 ubiquitin-protein ligase TRIP12

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in regulation of embryonic development IMP
IMP: Inferred from mutant phenotype
22028794 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIP12

  • HECT-type E3 ubiquitin transferase TRIP12

  • TR-interacting protein 12

  • gene trap locus 6

  • thyroid receptor interactor TRIP12

  • thyroid receptor-interacting protein 12

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15078 TRIP12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21965 Trip12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28482 Trip12 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trip12 NCBI NCBI:9320