Mst1 - macrophage stimulating 1 (hepatocyte growth factor-like) Gene

Also Known as Hgfl; D3F15S2h; DNF15S2h; D9H3F15S2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15235

Summary

Predicted to enable receptor tyrosine kinase binding activity. Acts upstream of or within several processes, including embryo implantation; mammary duct terminal end bud growth; and positive regulation of mammary gland epithelial cell proliferation. Located in vacuole. Is expressed in esophagus epithelium; liver; liver parenchyma; pharynx epithelium; and stomach proventricular region epithelium. Orthologous to several human genes including MST1 (macrophage stimulating 1). [provided by Alliance of Genome Resources, Apr 2022]

Mst1 Products (2)

mRNA Protein Name
NM_008243.3 NP_032269.3 hepatocyte growth factor-like protein precursor
NM_008243.3 NP_032269.3 hepatocyte growth factor-like protein precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within embryo implantation IDA
IDA: Inferred from direct assay
12606483 MGI
acts upstream of or within mammary duct terminal end bud growth IMP
IMP: Inferred from mutant phenotype
25049204 MGI
acts upstream of or within mammary gland development IMP
IMP: Inferred from mutant phenotype
25049204 MGI
acts upstream of or within negative regulation of epithelial cell apoptotic process IMP
IMP: Inferred from mutant phenotype
25049204 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
25049204 MGI
acts upstream of or within positive regulation of mammary gland epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
25049204 MGI
acts upstream of or within regulation of macrophage chemotaxis IMP
IMP: Inferred from mutant phenotype
25049204 MGI
acts upstream of or within regulation of receptor signaling pathway via JAK-STAT IMP
IMP: Inferred from mutant phenotype
25049204 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in vacuole IDA
IDA: Inferred from direct assay
25049204 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hepatocyte growth factor-like protein

  • MSP

  • macrophage stimulatory protein

Recombinant Mst1 Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P701103 MSP/MST1 Protein, Mouse (C677A, HEK293) P26928/NP_032269 (Q19-E716, C677A) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-132969 SBP-3264 Inhibitor 98.50% Unkown
HY-164595 IHMT-MST1-39 Inhibitor 99.68% Unkown
HY-186148 YL-602 Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mst1 NCBI NCBI:4485