SRFBP1 - serum response factor binding protein 1 Gene

Also Known as P49; Rlb1; BUD22; STRAP; p49/STRAP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 153443

About SRFBP1

Cytogenetic location: 5q23.1 Genomic coordinates (GRCh38): 5:121,961,975-122,078,935 (from NCBI)

This gene has 2 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in thyroid (RPKM 4.8), fat (RPKM 4.6) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of 90S preribosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SRFBP1 Products (1)

mRNA Protein Name
NM_152546.3 NP_689759.2 serum response factor-binding protein 1

SRFBP1 Protein Structure

BUD22

BUD22: BUD22 (369 - 428)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 429 a.a.
Protein Preferred Names Protein Names

serum response factor-binding protein 1

  • BUD22 homolog

Recombinant SRFBP1 Proteins

Cat. No. Product Name Accession Purity
HY-P77215 SRFBP1 Protein, Human (sf9, His-GST) Q8NEF9 (M1-D429) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Aortic Aneurysm, Familial Thoracic 10

  • AAT10

  • Aortic Aneurysm, Thoracic, With Or Without Aortic Dissection

  • Aneurysm, Aortic, Thoracic, Familial, Type 10
Aortic Aneurysm, Familial Thoracic 1

  • Thoracic Aortic Aneurysm

  • Annuloaortic Ectasia

  • Familial Thoracic Aortic Aneurysm And Aortic Dissection

  • Familial Aortic Dissection

  • Familial Taad

  • Familial Thoracic Aortic Aneurysm

  • Congenital Aneurysm Of Ascending Aorta

  • Familial Aortic Aneurysm

  • Familial Thoracic Aortic Aneurysm And Dissection

  • Aortic Aneurysm, Thoracic

  • AAT1

  • Faa1

  • Aortic Dissection, Familial

  • Aortic Aneurysm, Familial Thoracic

  • Aneurysm, Thoracic Aortic

  • Faa

  • Ftaad

  • Taa

  • Taad

  • Cystic Medial Necrosis Of Aorta

  • Familial Non-Syndromic Thoracic Aortic Aneurysm And Aortic Dissection

  • Aortic Aneurysm Thoracic

  • Familial Aortic Aneurysms

  • Aneurysm, Aortic, Thoracic, Familial, Type 1

  • Aneurysm Of Thoracic Aorta

  • Intrathoracic Aneurysm

  • Thoracic Aorta Aneurysm

  • Thoracic Aortic Aneurysm Without Rupture

  • Thoracic Aneurysm

  • Thorax Arterial Aneurysm

  • Thoracic Artery Aneurysm

  • Thoracic Arterial Aneurysm

  • Thorax Aneurysm

  • Thorax Aortic Aneurysm

  • Dissection Of Thoracic Aorta
Cutis Laxa

  • Generalized Elastolysis

  • Loose Skin

  • Dermatolysis

  • Dermatomegaly

  • Cutis Laxa Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13761 SRFBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20196 Srfbp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26701 Srfbp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SRFBP1 VGNC VGNC:77996
Mus musculus SRFBP1 MGD MGI:1914472
Rattus norvegicus SRFBP1 RGD RGD:1359398
Canis familiaris SRFBP1 VGNC VGNC:46800
Felis catus SRFBP1 VGNC VGNC:102335
Bos taurus SRFBP1 VGNC VGNC:55312
Others SRFBP1 NCBI