Hoxa3 - homeobox A3 Gene

Also Known as Mo-10; Hox-1.5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15400

Summary

Enables DNA-binding transcription factor activity and HMG box domain binding activity. Acts upstream of or within several processes, including animal organ development; blood vessel remodeling; and glossopharyngeal nerve morphogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; embryo mesenchyme; genitourinary system; gut; and nervous system. Used to study DiGeorge syndrome. Orthologous to human HOXA3 (homeobox A3). [provided by Alliance of Genome Resources, Apr 2022]

Hoxa3 Products (1)

mRNA Protein Name
NM_010452.4 NP_034582.1 homeobox protein Hox-A3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
21170035 MGI
enables HMG box domain binding IPI
IPI: Inferred from physical interaction
16582099 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within animal organ formation IMP
IMP: Inferred from mutant phenotype
7635047 MGI
acts upstream of or within animal organ morphogenesis IMP
IMP: Inferred from mutant phenotype
15100241 MGI
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
7913519 MGI
acts upstream of or within blood vessel remodeling IMP
IMP: Inferred from mutant phenotype
15714286 MGI
acts upstream of or within cartilage development IGI
IGI: Inferred from genetic interaction
9441667 MGI
acts upstream of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15714286 MGI
acts upstream of or within embryonic skeletal system development IGI
IGI: Inferred from genetic interaction
7913519 MGI
acts upstream of or within embryonic skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
9441667 MGI
acts upstream of gene expression IMP
IMP: Inferred from mutant phenotype
19968565 MGI
acts upstream of or within glossopharyngeal nerve morphogenesis IGI
IGI: Inferred from genetic interaction
9441667 MGI
acts upstream of or within glossopharyngeal nerve morphogenesis IMP
IMP: Inferred from mutant phenotype
9441667 MGI
acts upstream of or within parathyroid gland development IGI
IGI: Inferred from genetic interaction
11476574 MGI
acts upstream of or within positive regulation of stem cell proliferation IMP
IMP: Inferred from mutant phenotype
15714286 MGI
acts upstream of or within specification of animal organ position IGI
IGI: Inferred from genetic interaction
9520319 MGI
acts upstream of stem cell proliferation IMP
IMP: Inferred from mutant phenotype
15714286 MGI
acts upstream of or within thymus development IGI
IGI: Inferred from genetic interaction
9520319 MGI
acts upstream of or within thymus development IMP
IMP: Inferred from mutant phenotype
7635047 MGI
acts upstream of or within thyroid gland development IGI
IGI: Inferred from genetic interaction
9524238 MGI
acts upstream of or within thyroid gland development IMP
IMP: Inferred from mutant phenotype
7635047 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-A3

  • homeo box A3

  • homeobox protein Hox-1.5

  • homeobox protein MO-10

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06298 HOXA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22558 Hoxa3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29078 Hoxa3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxa3 NCBI NCBI:3200