Hoxb1 - homeobox B1 Gene

Also Known as Hox-2.9

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15407

Summary

Enables sequence-specific DNA binding activity. Contributes to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including central nervous system development; embryonic skeletal system morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; embryo ectoderm; embryo mesenchyme; and gut. Orthologous to human HOXB1 (homeobox B1). [provided by Alliance of Genome Resources, Apr 2022]

Hoxb1 Products (1)

mRNA Protein Name
NM_008266.5 NP_032292.3 homeobox protein Hox-B1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
7911971 MGI
contributes to RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
9242495 MGI
enables sequence-specific DNA binding IGI
IGI: Inferred from genetic interaction
18787068 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within anatomical structure formation involved in morphogenesis IGI
IGI: Inferred from genetic interaction
10529420 MGI
acts upstream of or within anatomical structure morphogenesis IGI
IGI: Inferred from genetic interaction
10529420 MGI
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
10529420 MGI
acts upstream of or within embryonic skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
10885747 MGI
acts upstream of or within facial nerve structural organization IMP
IMP: Inferred from mutant phenotype
8898234 MGI
acts upstream of or within facial nucleus development IMP
IMP: Inferred from mutant phenotype
8898234 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18787068 MGI
acts upstream of or within rhombomere 4 development IGI
IGI: Inferred from genetic interaction
10529420 MGI
acts upstream of or within rhombomere 5 development IGI
IGI: Inferred from genetic interaction
10529420 MGI
acts upstream of or within rhombomere development IDA
IDA: Inferred from direct assay
21320481 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-B1

  • homeo box B1

  • homeobox protein Hox-2.9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06304 HOXB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21596 Hoxb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28114 Hoxb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxb1 NCBI NCBI:3211