Hoxb3 - homeobox B3 Gene

Also Known as Hox-2.7

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15410

Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including animal organ development; face development; and nervous system development. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; gut; and skin. Orthologous to human HOXB3 (homeobox B3). [provided by Alliance of Genome Resources, Apr 2022]

Hoxb3 Products (2)

mRNA Protein Name
NM_001079869.1 NP_001073338.1 homeobox protein Hox-B3
NM_010458.2 NP_034588.2 homeobox protein Hox-B3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
21320481 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
9441667 MGI
acts upstream of or within cartilage development IGI
IGI: Inferred from genetic interaction
9441667 MGI
acts upstream of or within definitive hemopoiesis IGI
IGI: Inferred from genetic interaction
17761289 MGI
acts upstream of or within embryonic skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
9441667 MGI
acts upstream of or within embryonic skeletal system morphogenesis IMP
IMP: Inferred from mutant phenotype
9441667 MGI
acts upstream of or within face development IDA
IDA: Inferred from direct assay
21320481 MGI
acts upstream of or within glossopharyngeal nerve morphogenesis IGI
IGI: Inferred from genetic interaction
9441667 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IMP
IMP: Inferred from mutant phenotype
24029230 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
21320481 MGI
acts upstream of or within regulation of neurogenesis IDA
IDA: Inferred from direct assay
21320481 MGI
acts upstream of or within rhombomere development IDA
IDA: Inferred from direct assay
21320481 MGI
acts upstream of or within thyroid gland development IGI
IGI: Inferred from genetic interaction
9520319 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-B3

  • homeo box B3

  • homeobox protein Hox-2.7

  • homeobox protein MH-23

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS06307 HOXB3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21597 Hoxb3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28115 Hoxb3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxb3 NCBI NCBI:3213