Hoxb4 - homeobox B4 Gene

Also Known as Hox-2.6

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15412

Summary

Enables DNA binding activity. Acts upstream of or within several processes, including embryonic skeletal system morphogenesis; hematopoietic or lymphoid organ development; and somatic stem cell division. Predicted to be located in centrosome and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut; nervous system; and skin. Orthologous to human HOXB4 (homeobox B4). [provided by Alliance of Genome Resources, Apr 2022]

Hoxb4 Products (1)

mRNA Protein Name
NM_010459.7 NP_034589.3 homeobox protein Hox-B4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
7911971 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
7628700 MGI
acts upstream of or within bone marrow development IMP
IMP: Inferred from mutant phenotype
14962901 MGI
acts upstream of or within definitive hemopoiesis IGI
IGI: Inferred from genetic interaction
17761289 MGI
acts upstream of or within embryonic skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
7628700 MGI
acts upstream of or within hematopoietic stem cell proliferation IMP
IMP: Inferred from mutant phenotype
14962901 MGI
acts upstream of or within hemopoiesis IMP
IMP: Inferred from mutant phenotype
14962901 MGI
acts upstream of or within morphogenesis of an epithelial sheet IGI
IGI: Inferred from genetic interaction
11518511 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
8649375 MGI
acts upstream of or within skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
9012503 MGI
acts upstream of or within skeletal system morphogenesis IMP
IMP: Inferred from mutant phenotype
9012503 MGI
acts upstream of or within somatic stem cell division IDA
IDA: Inferred from direct assay
12717450 MGI
acts upstream of or within spleen development IMP
IMP: Inferred from mutant phenotype
14962901 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-B4

  • homeo box B4

  • homeobox protein Hox-2.6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12303 OAC1 Activator 99.85% Unkown
HY-RS06308 HOXB4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17008 Hoxb4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23451 Hoxb4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxb4 NCBI NCBI:3214