Hpx - hemopexin Gene

Also Known as hx; Hpxn

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15458

Summary

Predicted to enable heme binding activity. Acts upstream of or within several processes, including Hemoglobin metabolic process; positive regulation of immune response; and positive regulation of macromolecule metabolic process. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in brain; embryo; liver; liver left lobe; and liver right lobe. Orthologous to human HPX (hemopexin). [provided by Alliance of Genome Resources, Apr 2022]

Hpx Products (1)

mRNA Protein Name
NM_017371.2 NP_059067.2 hemopexin precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within heme metabolic process IMP
IMP: Inferred from mutant phenotype
18556779 MGI
acts upstream of or within hemoglobin metabolic process IMP
IMP: Inferred from mutant phenotype
10572107 MGI
acts upstream of or within positive regulation of humoral immune response mediated by circulating immunoglobulin IMP
IMP: Inferred from mutant phenotype
18641331 MGI
acts upstream of or within positive regulation of immunoglobulin production IMP
IMP: Inferred from mutant phenotype
18641331 MGI
acts upstream of or within positive regulation of response to type II interferon IMP
IMP: Inferred from mutant phenotype
18641331 MGI
acts upstream of or within positive regulation of type II interferon-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
18641331 MGI
acts upstream of or within positive regulation of tyrosine phosphorylation of STAT protein IMP
IMP: Inferred from mutant phenotype
18641331 MGI
acts upstream of or within regulation of protein metabolic process IMP
IMP: Inferred from mutant phenotype
10572107 MGI
acts upstream of type II interferon-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
18641331 MGI
acts upstream of tyrosine phosphorylation of STAT protein IMP
IMP: Inferred from mutant phenotype
18641331 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hemopexin

Recombinant Hpx Proteins

Cat. No. Product Name Accession Purity
HY-P70884 Hemopexin Protein, Mouse (HEK293, His, solution) Q91X72 (S24-Q460) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06352 HPX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18117 Hpx Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24591 Hpx Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hpx NCBI NCBI:3263