Hemopexin Protein, Mouse (HEK293, His, solution)
Based on 1 publication(s) in Google Scholar
Hemopexin Protein plays a crucial role in binding heme, transporting it to the liver for breakdown, and facilitating iron recovery. After this cycle, hemopexin re-enters circulation, emphasizing its pivotal role in regulating heme and iron homeostasis. Hemopexin Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived Hemopexin protein, expressed by HEK293 , with C-6*His labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
Hemopexin Protein plays a crucial role in binding heme, transporting it to the liver for breakdown, and facilitating iron recovery. After this cycle, hemopexin re-enters circulation, emphasizing its pivotal role in regulating heme and iron homeostasis. Hemopexin Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived Hemopexin protein, expressed by HEK293 , with C-6*His labeled tag.
Background
The Hemopexin Protein serves a vital function by binding to heme, facilitating its transport to the liver for breakdown, and enabling the recovery of iron. Following this process, the now free hemopexin re-enters the circulation, highlighting its role as a crucial mediator in the regulation of heme and iron homeostasis.
MCE Validation Data
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Purity - SDS-PAGE
Purity - SDS-PAGE
Publications (1)
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Journal Impact Factor
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Most Recent
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Biochim Biophys Acta Mol Basis Dis
Heme induced progesterone-resistant profiling and promotion of endometriosis in vitro and in vivo. [Abstract]2023 Oct;1869(7):166761. PMID: 37247698
Technical Parameters
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Species Mouse
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Source HEK293
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Tag C-6*His
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Accession
Q91X72 (S24-Q460)
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Molecular Construction
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N-term
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Hemopexin (S24-Q460)
Accession # Q91X72 -
6*His
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C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
HPX; Epididymis Secretory Sperm Binding Protein; Hemopexin; HX; Beta-1B-Glycoprotein
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AA Sequence
SPLPTANGRVAEVENGTKPDSDVPEHCLDTWSFDAATMDHNGTMLFFKGEFVWRGHSGTRELISARWKNPITSVDAAFRGPDSVFLIKEDKVWVYPPEKKENGYPKLFQEEFPGIPYPPDAAVECHRGECQSEGVLFFQGNRKWFWDFATRTQKERSWSTVGNCTAALRWLERYYCFQGNKFLRFNPVTGEVPPRYPLDARDYFVSCPGRGHGRPRNGTAHGNSTHPMHSRCSPDPGLTALLSDHRGATYAFTGSHYWRLDSSRDGWHSWPIAHHWPQGPSTVDAAFSWDDKVYLIQGTQVYVFLTKGGNNLVSGYPKRLEKELGSPPGISLETIDAAFSCPGSSRLYVSSGRRLWWLDLKSGAQATWTEVSWPHEKVDGALCLDKSLGPNTCSSNGSSLYFIHGPNLYCYSSIDKLNAAKSLPQPQKVNSILGCSQ
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Predicted Molecular Mass
49.8 kDa
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Molecular Weight
Approximately 65-90 kDa, based on SDS-PAGE under reducing conditions.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution
Supplied as a 0.22 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
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Data Sheet (237 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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