Hrh1 - histamine receptor H1 Gene

Mus musculus

Also known as H1R; Hir; Bphs; HH1R

Gene ID: 15465 | Gene type: protein coding

About Hrh1

Chromosome 6: 114,374,897-114,460,257 forward strand.GRCm39:CM000999.3

This gene has 5 transcripts (splice variants), 186 orthologues, 32 paralogues and is associated with 39 phenotypes. Biased expression in cortex adult (RPKM 2.2), colon adult (RPKM 1.7) and 14 other tissues.

Summary

Predicted to enable several functions, including G protein-coupled serotonin receptor activity; calcium ion transmembrane transporter activity; and histamine binding activity. Acts upstream of or within memory; regulation of synaptic plasticity; and visual learning. Predicted to be located in cytosol and plasma membrane. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Is expressed in brain; stomach; and uterus. Orthologous to human HRH1 (Histamine Receptor H1). [provided by Alliance of Genome Resources, Apr 2022]

Hrh1 Products(7)

mRNA	Protein	Name
NM_001252643.3	NP_001239572.1	histamine H1 receptor
NM_008285.5	NP_032311.2	histamine H1 receptor
NM_001252642.3	NP_001239571.1	histamine H1 receptor
NM_001317125.2	NP_001304054.1	histamine H1 receptor
NM_001317124.2	NP_001304053.1	histamine H1 receptor
NM_001410031.1	NP_001396960.1	histamine H1 receptor
NM_001317126.2	NP_001304055.1	histamine H1 receptor

Hrh1 Protein Structure

7tmA_Histamine_H1R

0
100
200
300
400
488 a.a.

Protein Preferred Names

Protein Names

histamine H1 receptor

Bordetella pertussis induced histamine sensitization

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS06359	HRH1 Human Pre-designed siRNA Set A	/	Unkown
HY-RS06360	Hrh1 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS06361	Hrh1 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hrh1	NCBI	NCBI:3269

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