2. Gene
  3. Hsph1 - heat shock 105kDa/110kDa protein 1 Gene

Hsph1 - heat shock 105kDa/110kDa protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 105kDa; Hsp105; Hsp110; hsp-E7I; hsp110/105

Gene ID: 15505 | Gene type: protein coding

About Hsph1

Chromosome 5: 149,537,752-149,559,841 reverse strand.GRCm39:CM000998.3

This gene has 11 transcripts (splice variants), 158 orthologues, 12 paralogues and is associated with 3 phenotypes. Broad expression in cortex adult (RPKM 3.2), CNS E11.5 (RPKM 29.9) and 25 other tissues.

Summary

Enables alpha-tubulin binding activity. Acts upstream of or within several processes, including chaperone cofactor-dependent protein refolding; negative regulation of intracellular signal transduction; and positive regulation of nitrogen compound metabolic process. Located in cytoplasm and nucleus. Colocalizes with microtubule. Is expressed in several structures, including brain; gut; integumental system; liver and biliary system; and reproductive system. Orthologous to human HSPH1 (heat shock protein family H (Hsp110) member 1). [provided by Alliance of Genome Resources, Apr 2022]

Hsph1 Products(2)

mRNA Protein Name
NM_013559.2 NP_038587.2 heat shock protein 105 kDa isoform 1
NM_001347534.1 NP_001334463.1 heat shock protein 105 kDa isoform 2

Hsph1 Protein Structure

HSPH1_NBD

HSPH1_NBD: cd11739 (1 - 383)

FtsN

FtsN: cl34549 (517 - 600)

  • 0
  • 200
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  • 800
  • 858 a.a.
Protein Preferred Names Protein Names

heat shock protein 105 kDa

42 degrees C-HSP

HSP105 42 C-HSP

heat shock 110 kDa protein

heat shock protein 110

heat shock-related 100 kDa protein E7I

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06450 HSPH1 Human Pre-designed siRNA Set A / Unkown
HY-RS06451 Hsph1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS06452 Hsph1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsph1 NCBI NCBI:10808