Il23a - interleukin 23 subunit alpha Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 155140

About Il23a

Primary_assembly 7: 721,809-723,923 reverse strand.mRatBN7.2:CM026980.1

This gene has 1 transcript (splice variant), 96 orthologues and is associated with 23 phenotypes. Biased expression in Thymus (RPKM 15.2), Spleen (RPKM 11.9) and 9 other tissues.

Summary

Predicted to enable cytokine activity. Predicted to contribute to interleukin-23 receptor binding activity. Predicted to be involved in several processes, including positive regulation of cytokine production; positive regulation of lymphocyte activation; and positive regulation of peptidyl-tyrosine phosphorylation. Predicted to act upstream of or within T cell proliferation and positive regulation of transcription by RNA polymerase II. Predicted to be located in extracellular space. Predicted to be part of interleukin-23 complex. Orthologous to human IL23A (interleukin 23 subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Il23a Products (1)

mRNA Protein Name
NM_130410.2 NP_569094.1 interleukin-23 subunit alpha precursor

Il23a Protein Structure

IL23

IL23: pfam16649 (27 - 184)

  • 0
  • 100
  • 196 a.a.
Protein Preferred Names Protein Names

interleukin-23 subunit alpha

  • IL-23 subunit alpha

  • IL-23-A

  • IL-23p19

  • Interleukin 23, alpha subunit p19

  • interleukin-23 subunit p19

Recombinant Il23a Proteins

Cat. No. Product Name Accession Purity
HY-P73195 IL-23 Protein, Rat (HEK293, His) NP_569094.1 (V22-A196) & EDM04146.1 (M23-S335) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990057 Picankibart Inhibitor 98.00% Phase 3

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-176535 KB-0118 Inhibitor / Unkown
HY-RS06739 IL23A Human Pre-designed siRNA Set A / Unkown
HY-RS06740 Il23a Mouse Pre-designed siRNA Set A / Unkown
HY-RS06741 Il23a Rat Pre-designed siRNA Set A / Unkown
HY-174616 Human IL23R mRNA / Unkown
HY-174617 Human IL23A mRNA / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il23a NCBI NCBI:51561