Htr5a - 5-hydroxytryptamine (serotonin) receptor 5A Gene

Also Known as Htr5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15563

About Htr5a

Chromosome 5: 28,047,147-28,060,086 forward strand.GRCm39:CM000998.3

This gene has 1 transcript (splice variant), 215 orthologues, 9 paralogues and is associated with 3 phenotypes. Biased expression in cortex adult (RPKM 2.1), frontal lobe adult (RPKM 2.) and 4 other tissues.

Summary

Predicted to enable G protein-coupled serotonin receptor activity; neurotransmitter receptor activity; and serotonin binding activity. Acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in Golgi apparatus; perikaryon; and rough endoplasmic reticulum. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Is expressed in several structures, including adipose tissue; brain; eye; female reproductive system; and gut. Orthologous to human HTR5A (5-hydroxytryptamine receptor 5A). [provided by Alliance of Genome Resources, Apr 2022]

Htr5a Products (1)

mRNA Protein Name
NM_008314.2 NP_032340.2 5-hydroxytryptamine receptor 5A

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
11406289 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Htr5a Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (40 - 348)

7tm_GPCRs

7tm_GPCRs: cd14964 (42 - 66)

7tm_GPCRs

7tm_GPCRs: cd14964 (75 - 97)

7tm_GPCRs

7tm_GPCRs: cd14964 (114 - 136)

7tm_GPCRs

7tm_GPCRs: cd14964 (159 - 175)

7tm_GPCRs

7tm_GPCRs: cd14964 (197 - 220)

7tm_GPCRs

7tm_GPCRs: cd14964 (283 - 305)

7tm_GPCRs

7tm_GPCRs: cd14964 (316 - 341)

  • 0
  • 100
  • 200
  • 300
  • 357 a.a.
Protein Preferred Names Protein Names

5-hydroxytryptamine receptor 5A

  • 5-HT-5

  • 5-HT-5A

  • 5-HT5A

  • serotonin receptor 5A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06477 HTR5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06478 Htr5a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06479 Htr5a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Htr5a NCBI NCBI:3361