Itgax - integrin alpha X Gene

Also Known as Cr4; N418; Cd11c

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16411

Summary

Predicted to enable receptor tyrosine kinase binding activity. Involved in positive regulation of gene expression and positive regulation of myelination. Acts upstream of or within defense response to virus. Located in external side of plasma membrane. Is expressed in heart and hemolymphoid system. Orthologous to human ITGAX (Integrin subunit alpha X). [provided by Alliance of Genome Resources, Apr 2022]

Itgax Products (3)

mRNA Protein Name
NM_001363984.1 NP_001350913.1 integrin alpha-X isoform 2 precursor
NM_001363985.1 NP_001350914.1 integrin alpha-X isoform 3 precursor
NM_021334.3 NP_067309.1 integrin alpha-X isoform 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
NOT acts upstream of or within activated T cell proliferation IMP
IMP: Inferred from mutant phenotype
15210787 MGI
acts upstream of or within defense response to virus IDA
IDA: Inferred from direct assay
17277142 MGI
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
28963396 MGI
involved in positive regulation of myelination IDA
IDA: Inferred from direct assay
28963396 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
1385153 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrin alpha-X

  • CD11 antigen-like family member C

  • CD11C (p150) alpha polypeptide

  • complement receptor 4

  • integrin aX

  • leukocyte adhesion glycoprotein p150,95 alpha chain

  • leukocyte adhesion receptor p150,95

Itgax Antibodies

Cat. No. Product Name Application Reactivity
HY-P83713M CD11c Antibody (APC)(YA3450) FC Mouse
HY-P83768 CD11c Antibody(YA3565) WB, IHC-P, IHC-F, IF-Tissue Mouse

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06962 ITGAX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17766 Itgax Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24233 Itgax Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29095 Itgad Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itgax NCBI NCBI:3687