Kif3b - kinesin family member 3B Gene

Also Known as mKIAA0359

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16569

Summary

Enables intraciliary transport particle B binding activity. Involved in anterograde dendritic transport of neurotransmitter receptor complex; cilium assembly; and vesicle-mediated transport. Located in centrosome; cilium; and dendrite. Part of Kinesin II complex. Is expressed in several structures, including central nervous system; gonad; gut; hemolymphoid system gland; and nose. Used to study schizophrenia. Human ortholog(s) of this gene implicated in retinitis pigmentosa 89. Orthologous to human KIF3B (Kinesin family member 3B). [provided by Alliance of Genome Resources, Apr 2022]

Kif3b Products (1)

mRNA Protein Name
NM_008444.4 NP_032470.3 kinesin-like protein KIF3B

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables intraciliary transport particle B binding IDA
IDA: Inferred from direct assay
12821668 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12821668 MGI
Biological Process GO Annotation Evidence References Source
involved in anterograde dendritic transport of neurotransmitter receptor complex IDA
IDA: Inferred from direct assay
31746486 MGI
involved in anterograde dendritic transport of neurotransmitter receptor complex IMP
IMP: Inferred from mutant phenotype
31746486 MGI
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
9865700 MGI
involved in vesicle-mediated transport IMP
IMP: Inferred from mutant phenotype
31746486 MGI
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
19253336 MGI
located in cilium IDA
IDA: Inferred from direct assay
9865700 MGI
located in dendrite IDA
IDA: Inferred from direct assay
31746486 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
31746486 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
31746486 MGI
part of kinesin II complex IDA
IDA: Inferred from direct assay
19384852 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
31746486 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kinesin-like protein KIF3B

  • microtubule plus end-directed kinesin motor 3B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-175496 Acid Ceramidase-IN-3 Inhibitor / Unkown
HY-182741 RET-IN-32 Inhibitor / Unkown
HY-RS07286 KIF3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22596 Kif3b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29113 Kif3b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kif3b NCBI NCBI:9371