Xcl1 - chemokine (C motif) ligand 1 Gene

Also Known as LTN; ATAC; Lptn; SCM-1; Scyc1; SCM-1a

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16963

Summary

Enables chemokine activity. Involved in several processes, including mature natural killer cell chemotaxis; positive regulation of leukocyte migration; and positive regulation of production of molecular mediator of immune response. Acts upstream of or within chemotaxis and release of sequestered calcium ion into cytosol. Located in extracellular space. Orthologous to several human genes including XCL1 (X-C motif chemokine ligand 1). [provided by Alliance of Genome Resources, Apr 2022]

Xcl1 Products (1)

mRNA Protein Name
NM_008510.3 NP_032536.1 lymphotactin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chemokine activity IDA
IDA: Inferred from direct assay
7973732 MGI
enables chemokine receptor binding IDA
IDA: Inferred from direct assay
9632725 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to interleukin-4 IDA
IDA: Inferred from direct assay
9013979 MGI
involved in cellular response to transforming growth factor beta stimulus IDA
IDA: Inferred from direct assay
9013979 MGI
acts upstream of or within chemotaxis IDA
IDA: Inferred from direct assay
10518929 MGI
acts upstream of or within establishment of localization in cell IDA
IDA: Inferred from direct assay
10518929 MGI
involved in mature natural killer cell chemotaxis IDA
IDA: Inferred from direct assay
9029087 MGI
involved in positive regulation of B cell chemotaxis IDA
IDA: Inferred from direct assay
11181058 MGI
involved in positive regulation of CD4-positive, alpha-beta T cell proliferation IDA
IDA: Inferred from direct assay
9973465 MGI
involved in positive regulation of T cell chemotaxis IDA
IDA: Inferred from direct assay
8757601 MGI
involved in positive regulation of T cell cytokine production IDA
IDA: Inferred from direct assay
9029087 MGI
involved in positive regulation of T-helper 1 cell cytokine production IDA
IDA: Inferred from direct assay
9973465 MGI
involved in positive regulation of T-helper 2 cell cytokine production IDA
IDA: Inferred from direct assay
9973465 MGI
involved in positive regulation of immunoglobulin production in mucosal tissue IDA
IDA: Inferred from direct assay
9973465 MGI
involved in positive regulation of leukocyte chemotaxis IDA
IDA: Inferred from direct assay
7973732 MGI
involved in positive regulation of natural killer cell chemotaxis IDA
IDA: Inferred from direct assay
9029087 MGI
involved in positive regulation of neutrophil chemotaxis IDA
IDA: Inferred from direct assay
11181058 MGI
involved in positive regulation of thymocyte migration IDA
IDA: Inferred from direct assay
7973732 MGI
acts upstream of or within release of sequestered calcium ion into cytosol IDA
IDA: Inferred from direct assay
10518929 MGI
involved in release of sequestered calcium ion into cytosol IDA
IDA: Inferred from direct assay
7973732 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
9973465 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lymphotactin

  • c motif chemokine 1

  • chemokine XCL1

  • cytokine SCM-1

  • lymphotaxin

  • small inducible cytokine subfamily C, member 1 (lymphotactin)

  • small-inducible cytokine C1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15866 XCL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16940 Xcl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23383 Xcl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xcl1 NCBI NCBI:6375