Cysltr2 - cysteinyl leukotriene receptor 2 Gene

Rattus norvegicus

Also known as Cyslt2; RSBPT32

Gene ID: 170926 | Gene type: protein coding

About Cysltr2

Primary_assembly 15: 48,189,073-48,304,136 reverse strand.mRatBN7.2:CM026988.1

This gene has 5 transcripts (splice variants), 55 orthologues, 13 paralogues and is associated with 12 phenotypes. Biased expression in Thymus (RPKM 57.3), Lung (RPKM 32.) and 4 other tissues.

Summary

Predicted to enable G protein-coupled peptide receptor activity and cysteinyl Leukotriene Receptor activity. Involved in positive regulation of ERK1 and ERK2 cascade; positive regulation of angiogenesis; and positive regulation of cell death. Predicted to be located in membrane. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in aspirin-induced respiratory disease and asthma. Orthologous to human CYSLTR2 (cysteinyl Leukotriene Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Cysltr2 Products(1)

mRNA	Protein	Name
NM_133413.2	NP_596904.1	cysteinyl leukotriene receptor 2

Cysltr2 Protein Structure

7tm_GPCRs

0
100
200
309 a.a.

Protein Preferred Names

Protein Names

cysteinyl leukotriene receptor 2

cysteinyl leukotriene CysLT2 receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS03497	CYSLTR2 Human Pre-designed siRNA Set A	/	Unkown
HY-RS03498	Cysltr2 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS03499	Cysltr2 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cysltr2	NCBI	NCBI:57105

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