2. Gene
  3. Ctsd - cathepsin D Gene

Ctsd - cathepsin D Gene

  • Gene
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 171293 | Gene type: protein coding

About Ctsd

Primary_assembly 1: 197,527,467-197,539,488 reverse strand.mRatBN7.2:CM026974.1

This gene has 3 transcripts (splice variants), 211 orthologues, 8 paralogues and is associated with 21 phenotypes.

Summary

Enables endopeptidase activity and peptide binding activity. Involved in proteolysis and response to nutrient levels. Located in lysosome. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; and neuronal ceroid lipofuscinosis 10. Orthologous to human CTSD (Cathepsin D). [provided by Alliance of Genome Resources, Apr 2022]

Ctsd Products(1)

mRNA Protein Name
NM_134334.3 NP_599161.2 cathepsin D precursor

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-137978A Ezurpimtrostat hydrochloride Inhibitor 98.29% Phase 2
HY-137978 Ezurpimtrostat Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03328 CTSD Human Pre-designed siRNA Set A / Unkown
HY-RS03329 Ctsd Mouse Pre-designed siRNA Set A / Unkown
HY-RS03330 Ctsd Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctsd NCBI NCBI:1509
Mus musculus Ctsd NCBI NCBI:13033