Cxcl3 - C-X-C motif chemokine ligand 3 Gene

Also Known as Cinc2; Cinc-2; Gm1960

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171551

Summary

Enables chemokine activity. Involved in several processes, including cellular response to lipopolysaccharide; neutrophil chemotaxis; and positive regulation of cytosolic calcium ion concentration. Located in extracellular space. Biomarker of Coronavirus infectious disease and Bacterial pneumonia. Orthologous to human CXCL1 (C-X-C motif chemokine ligand 1); CXCL2 (C-X-C motif chemokine ligand 2); and CXCL3 (C-X-C motif chemokine ligand 3). [provided by Alliance of Genome Resources, Apr 2022]

Cxcl3 Products (1)

mRNA Protein Name
NM_001394590.1 NP_001381519.1 C-X-C motif chemokine 3 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chemokine activity IDA
IDA: Inferred from direct assay
8043001 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
10738946 RGD
involved in neutrophil chemotaxis IDA
IDA: Inferred from direct assay
8043001 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
10975996 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
15045510 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
18391855 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-X-C motif chemokine 3

  • MIP2-alpha/beta

  • chemokine (C-X-C motif) ligand 3

  • cytokine-induced neutrophil chemoattractant 2

  • macrophage inflammatory protein 2-alpha/beta

Recombinant Cxcl3 Proteins

Cat. No. Product Name Accession Purity
HY-P7152 CXCL3/CINC-2 alpha Protein, Rat (CHO) Q10746-1 (R33-S100) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03392 CXCL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-110268 NVP CXCR2 20 Antagonist / Unkown
HY-168971 Paeoniflorin-6′-O-benzene sulfonate / Unkown
HY-RS17078 Cxcl3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23522 Cxcl3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cxcl3 NCBI NCBI:2921