Masp1 - mannan-binding lectin serine peptidase 1 Gene

Also Known as CCPII; Crarf; Masp1/3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17174

Summary

Enables serine-type endopeptidase activity. Involved in complement activation, lectin pathway. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver; and spleen. Human ortholog(s) of this gene implicated in 3MC syndrome 1. Orthologous to human MASP1 (MBL associated serine protease 1). [provided by Alliance of Genome Resources, Apr 2022]

Masp1 Products (2)

mRNA Protein Name
NM_001359083.1 NP_001346012.1 mannan-binding lectin serine protease 1 isoform 1 precursor
NM_008555.3 NP_032581.2 mannan-binding lectin serine protease 1 isoform 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables serine-type endopeptidase activity IDA
IDA: Inferred from direct assay
18424734 MGI
Biological Process GO Annotation Evidence References Source
involved in complement activation, lectin pathway IMP
IMP: Inferred from mutant phenotype
18424734 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
18424734 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mannan-binding lectin serine protease 1

  • MASP-1

  • complement factor MASP-3

  • complement-activating component of Ra-reactive factor

  • mannose-binding lectin-associated serine protease 1

  • mannose-binding protein-associated serine protease

  • ra-reactive factor serine protease p100

  • raRF

  • serine proteas

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11596 NOTA-Asp2-αvβ6L / Unkown
HY-RS08159 MASP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17421 Masp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23876 Masp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Masp1 NCBI NCBI:5648