Mbd1 - methyl-CpG binding domain protein 1 Gene

Also Known as PCM1; Cxxc3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17190

Summary

Enables DNA binding activity. Predicted to be involved in negative regulation of astrocyte differentiation and negative regulation of gene expression. Located in cytoplasm; heterochromatin; and nuclear lumen. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and retina. Human ortholog(s) of this gene implicated in lung Cancer. Orthologous to human MBD1 (methyl-CpG binding domain protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Mbd1 Products (10)

mRNA Protein Name
NM_001357421.2 NP_001344350.1 methyl-CpG-binding domain protein 1 isoform 2
NM_001357422.2 NP_001344351.1 methyl-CpG-binding domain protein 1 isoform 3
NM_001357423.2 NP_001344352.1 methyl-CpG-binding domain protein 1 isoform 4
NM_001402889.1 NP_001389818.1 methyl-CpG-binding domain protein 1 isoform 5
NM_001402890.1 NP_001389819.1 methyl-CpG-binding domain protein 1 isoform 6
NM_001402891.1 NP_001389820.1 methyl-CpG-binding domain protein 1 isoform 7
NM_001402892.1 NP_001389821.1 methyl-CpG-binding domain protein 1 isoform 8
NM_001402894.1 NP_001389823.1 methyl-CpG-binding domain protein 1 isoform 9
NM_001402895.1 NP_001389824.1 methyl-CpG-binding domain protein 1 isoform 10
NM_013594.4 NP_038622.2 methyl-CpG-binding domain protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
9774669 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15777793 MGI
Cellular Component GO Annotation Evidence References Source
located in chromatin IDA
IDA: Inferred from direct assay
9774669 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
17546630 MGI
located in heterochromatin IDA
IDA: Inferred from direct assay
14519686 MGI
located in nuclear matrix IDA
IDA: Inferred from direct assay
15777793 MGI
located in nuclear speck IDA
IDA: Inferred from direct assay
15777793 MGI
NOT located in nucleolus IDA
IDA: Inferred from direct assay
17546630 MGI
located in nucleus IDA
IDA: Inferred from direct assay
9774669 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methyl-CpG-binding domain protein 1

  • methyl-CpG-binding protein MBD1

Mbd1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P86957 MBD1 Antibody (YA6650) WB, ICC/IF, FC Mouse, Rat

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-159978 EOS789 Inhibitor 99.14% Phase 1

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03947 DPEP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08181 MBD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22228 Mbd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28750 Mbd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mbd1 NCBI NCBI:4152