Mbl2 - mannose-binding lectin (protein C) 2 Gene

Also Known as MBL; L-MBP; MBL-C; MBP-C; RARF/P28A

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17195

Summary

Predicted to enable several functions, including calcium-dependent protein binding activity; identical protein binding activity; and mannose binding activity. Acts upstream of or within defense response to Other organism and positive regulation of phagocytosis. Located in extracellular space. Is expressed in embryo. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); Bacterial infectious disease (multiple); Fungal infectious disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human MBL2 (mannose binding lectin 2). [provided by Alliance of Genome Resources, Apr 2022]

Mbl2 Products (2)

mRNA Protein Name
NM_001365058.1 NP_001351987.1 mannose-binding protein C precursor
NM_010776.2 NP_034906.1 mannose-binding protein C precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within complement activation, lectin pathway IDA
IDA: Inferred from direct assay
15148336 MGI
acts upstream of or within complement activation, lectin pathway IGI
IGI: Inferred from genetic interaction
15148336 MGI
acts upstream of or within complement activation, lectin pathway IMP
IMP: Inferred from mutant phenotype
15148336 MGI
acts upstream of or within defense response to Gram-positive bacterium IGI
IGI: Inferred from genetic interaction
15148336 MGI
acts upstream of or within killing by host of symbiont cells IGI
IGI: Inferred from genetic interaction
15148336 MGI
acts upstream of or within positive regulation of phagocytosis IGI
IGI: Inferred from genetic interaction
15148336 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
15148336 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mannose-binding protein C

  • RA-reactive factor P28A subunit

  • mannan-binding protein

  • mannose binding lectin, liver (C)

Recombinant Mbl2 Proteins

Cat. No. Product Name Accession Purity
HY-P70674 MBL2/COLEC1 Protein, Mouse (HEK293) Q3UEK1 (E19-D244) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08188 MBL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18484 Mbl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24966 Mbl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mbl2 NCBI NCBI:4153