Mcm6 - minichromosome maintenance complex component 6 Gene

Also Known as Mcmd6; ASP-l1; D1Wsu22e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17219

Summary

Enables single-stranded DNA binding activity. Contributes to DNA helicase activity. Acts upstream of or within DNA unwinding involved in DNA replication. Located in nucleus. Is expressed in several structures, including brain; eye; future brain; genitourinary system; and limb. Orthologous to human MCM6 (minichromosome maintenance complex component 6). [provided by Alliance of Genome Resources, Apr 2022]

Mcm6 Products (2)

mRNA Protein Name
NM_001313695.1 NP_001300624.1 DNA replication licensing factor MCM6 isoform 2
NM_008567.2 NP_032593.1 DNA replication licensing factor MCM6 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to DNA helicase activity IDA
IDA: Inferred from direct assay
12207017 MGI
contributes to DNA helicase activity IMP
IMP: Inferred from mutant phenotype
10567526 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12192004 MGI
contributes to single-stranded DNA binding IDA
IDA: Inferred from direct assay
12207017 MGI
contributes to single-stranded DNA binding IMP
IMP: Inferred from mutant phenotype
10567526 MGI
enables single-stranded DNA binding IPI
IPI: Inferred from physical interaction
15917436 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within DNA unwinding involved in DNA replication IPI
IPI: Inferred from physical interaction
15917436 MGI
Cellular Component GO Annotation Evidence References Source
part of MCM complex IDA
IDA: Inferred from direct assay
10567526 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11555636 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA replication licensing factor MCM6

  • mini chromosome maintenance deficient 6

  • minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N4148 Purpureaside C Inducer 99.40% Unkown
HY-RS08239 MCM6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21372 Mcm6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27891 Mcm6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mcm6 NCBI NCBI:4175