Foxk1 - forkhead box K1 Gene

Also Known as Mnf; Gm10868; A630048H08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17425

Summary

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of cell growth; negative regulation of transcription, DNA-templated; and positive regulation of transcription, DNA-templated. Acts upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system; and retina. Orthologous to human FOXK1 (forkhead box K1). [provided by Alliance of Genome Resources, Apr 2022]

Foxk1 Products (1)

mRNA Protein Name
NM_199068.2 NP_951031.2 forkhead box protein K1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
9271401 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
9271401 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
9271401 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10620510 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
8007964 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
9271401 MGI
involved in negative regulation of cell growth IDA
IDA: Inferred from direct assay
10620510 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
8007964 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9271401 MGI
involved in regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9271401 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

forkhead box protein K1

  • myocyte nuclear factor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05059 FOXK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20929 Foxk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27446 Foxk1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Foxk1 NCBI NCBI:221937