Mtnr1a - melatonin receptor 1A Gene

Mus musculus

Also known as MR; MelR

Gene ID: 17773 | Gene type: protein coding

About Mtnr1a

Chromosome 8: 45,522,174-45,541,543 forward strand.GRCm39:CM001001.3

This gene has 3 transcripts (splice variants), 185 orthologues, 55 paralogues and is associated with 8 phenotypes. Biased expression in testis adult (RPKM 1.3), liver adult (RPKM .1) and 3 other tissues.

Summary

Predicted to enable hormone binding activity; Melatonin Receptor activity; and organic cyclic compound binding activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; circadian rhythm; and negative regulation of Insulin secretion. Predicted to act upstream of or within signal transduction. Predicted to be located in neuronal cell body. Predicted to be integral component of plasma membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; brain; gonad; intestine; and liver and biliary system. Orthologous to human MTNR1A (Melatonin Receptor 1A). [provided by Alliance of Genome Resources, Apr 2022]

Mtnr1a Products(1)

mRNA	Protein	Name
NM_008639.3	NP_032665.1	melatonin receptor type 1A

Mtnr1a Protein Structure

7tm_GPCRs

0
100
200
300
353 a.a.

Protein Preferred Names

Protein Names

melatonin receptor type 1A

Mel1a receptor

mel-1A-R

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Purity	Rare Diseases
HY-145700	UCSF648	/	Unkown
HY-RS08803	MTNR1A Human Pre-designed siRNA Set A	/	Unkown
HY-RS08804	Mtnr1a Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS08805	Mtnr1a Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mtnr1a	NCBI	NCBI:4543

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