Mtnr1a - melatonin receptor 1A Gene
Also Known as MR; MelR
Species: Mus musculus
About Mtnr1a
This gene has 3 transcripts (splice variants), 185 orthologues, 55 paralogues and is associated with 8 phenotypes. Biased expression in testis adult (RPKM 1.3), liver adult (RPKM .1) and 3 other tissues.
Summary
Predicted to enable hormone binding activity; Melatonin Receptor activity; and organic cyclic compound binding activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; circadian rhythm; and negative regulation of Insulin secretion. Predicted to act upstream of or within signal transduction. Predicted to be located in neuronal cell body. Predicted to be integral component of plasma membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; brain; gonad; intestine; and liver and biliary system. Orthologous to human MTNR1A (Melatonin Receptor 1A). [provided by Alliance of Genome Resources, Apr 2022]
Mtnr1a Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_008639.3 | NP_032665.1 | melatonin receptor type 1A |
Mtnr1a Protein Structure
7tm_GPCRs: cl28897 (30 - 308)
7tm_GPCRs: cd14964 (32 - 56)
7tm_GPCRs: cd14964 (65 - 87)
7tm_GPCRs: cd14964 (103 - 125)
7tm_GPCRs: cd14964 (148 - 164)
7tm_GPCRs: cd14964 (187 - 210)
7tm_GPCRs: cd14964 (239 - 261)
7tm_GPCRs: cd14964 (276 - 301)
- 0
- 100
- 200
- 300
- 353 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
melatonin receptor type 1A |
|