Ncoa3 - nuclear receptor coactivator 3 Gene

Also Known as Actr; Aib1; Rac3; Src3; pCip; Tram1; p/Cip; KAT13B; Tram-1; bHLHe42; 2010305B15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17979

Summary

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II complex binding activity; and nuclear receptor coactivator activity. Involved in cell dedifferentiation; positive regulation of stem cell population maintenance; and regulation of stem cell division. Acts upstream of or within several processes, including mammary gland branching involved in thelarche; negative regulation of stem cell differentiation; and reproductive structure development. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including brain; early conceptus; genitourinary system; hemolymphoid system; and sensory organ. Human ortholog(s) of this gene implicated in obesity. Orthologous to human NCOA3 (nuclear receptor coactivator 3). [provided by Alliance of Genome Resources, Apr 2022]

Ncoa3 Products (4)

mRNA Protein Name
NM_001374779.1 NP_001361708.1 nuclear receptor coactivator 3 isoform 2
NM_001405160.1 NP_001392089.1 nuclear receptor coactivator 3 isoform 3
NM_001405161.1 NP_001392090.1 nuclear receptor coactivator 3 isoform 4
NM_008679.4 NP_032705.2 nuclear receptor coactivator 3 isoform 1
Protein Preferred Names Protein Names

nuclear receptor coactivator 3

  • AIB-1

  • CBP-interacting protein

  • NCoA-3

  • RAC-3

  • SRC-3

  • amplified in breast cancer-1 protein homolog

  • receptor-associated coactivator 3

  • steroid receptor coactivator protein 3

  • thyroid hormone receptor activator molecule 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09091 NCOA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-173033 MI-883 99.57% Unkown
HY-P11829 ACTR-AD1 2L Inhibitor / Unkown
HY-RS20451 Ncoa3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26960 Ncoa3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ncoa3 NCBI NCBI:8202