Neu1 - neuraminidase 1 Gene

Also Known as G9; Apl; Neu; Aglp; Bat7; Bat-7; Map-2; Neu-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18010

Summary

Enables exo-alpha-sialidase activity. Predicted to be involved in several processes, including ganglioside catabolic process; positive regulation of neuron projection development; and regulation of myoblast proliferation. Predicted to act upstream of or within carbohydrate metabolic process and lipid catabolic process. Located in lysosome. Is expressed in alimentary system; brain; intestine; midgut; and midgut loop. Used to study glycoproteinosis. Orthologous to human NEU1 (neuraminidase 1). [provided by Alliance of Genome Resources, Apr 2022]

Neu1 Products (1)

mRNA Protein Name
NM_010893.3 NP_035023.3 sialidase-1 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables exo-alpha-sialidase activity IDA
IDA: Inferred from direct assay
9425240 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9425240 MGI
Cellular Component GO Annotation Evidence References Source
located in lysosome IDA
IDA: Inferred from direct assay
9425240 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sialidase-1

  • G9 sialidase

  • HLA-B-associated transcript 7

  • N-acetyl-alpha-neuraminidase 1

  • lysosomal sialidase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-125798 2,3-Dehydro-2-deoxy-N-acetylneuraminic acid Inhibitor ≥99.0% Unkown
HY-161943 NEU3-IN-1 98.74% Unkown
HY-169155 OsMo / Unkown
HY-RS04206 EGFL7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09215 NEU1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09219 NEURL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-183400 BIM-46174 / Unkown
HY-RS18959 Neu1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25449 Neu1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Neu1 NCBI NCBI:4758