Nfe2l3 - nuclear factor, erythroid derived 2, like 3 Gene

Also Known as Nrf3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18025

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in brain; forelimb bud; gonad; and ureter. Orthologous to human NFE2L3 (NFE2 like bZIP transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Nfe2l3 Products (1)

mRNA Protein Name
NM_010903.2 NP_035033.1 nuclear factor erythroid 2-related factor 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
15385560 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
15385560 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
15385560 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15385560 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear factor erythroid 2-related factor 3

  • NF-E2-related factor 3

  • NFE2-related factor 3

  • nuclear factor erythroid 2-like 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS19795 Nfe2l3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09248 NFE2L3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26291 Nfe2l3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nfe2l3 NCBI NCBI:9603