2. Gene
  3. NFE2L3 - NFE2 like bZIP transcription factor 3 Gene

NFE2L3 - NFE2 like bZIP transcription factor 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as NRF3

Gene ID: 9603 | Gene type: protein coding

About NFE2L3

Cytogenetic location: 7p15.2 Genomic coordinates (GRCh38): 7:26,152,198-26,187,137 (from NCBI)

This gene has 3 transcripts (splice variants), 193 orthologues and 3 paralogues. Broad expression in placenta (RPKM 30.4), appendix (RPKM 7.6) and 16 other tissues.

Summary

This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009]

NFE2L3 Products(1)

mRNA Protein Name
NM_004289.7 NP_004280.5 nuclear factor erythroid 2-related factor 3

NFE2L3 Protein Structure

bZIP_Maf

bZIP_Maf: bZIP Maf transcription factor (549 - 638)

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  • 600
  • 694 a.a.
Protein Preferred Names Protein Names

nuclear factor erythroid 2-related factor 3

NF-E2-related factor 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09248 NFE2L3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus NFE2L3 MGD MGI:1339958
Rattus norvegicus NFE2L3 RGD RGD:1307730
Bos taurus NFE2L3 VGNC VGNC:32037
Canis familiaris NFE2L3 VGNC VGNC:43774
Macaca mulatta NFE2L3 VGNC VGNC:75333
Felis catus NFE2L3 VGNC VGNC:68476