Nqo2 - N-ribosyldihydronicotinamide quinone reductase 2 Gene
Also Known as Ox2; NMO2; Nmor2
Species: Mus musculus
Summary
Predicted to enable several functions, including anion binding activity; dihydronicotinamide riboside Quinone Reductase activity; and melatonin binding activity. Predicted to be involved in several processes, including positive regulation of ERK1 and ERK2 cascade; positive regulation of neuron apoptotic process; and positive regulation of vascular associated smooth muscle cell proliferation. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in adenohypophysis. Human ortholog(s) of this gene implicated in Parkinson's disease; agranulocytosis; breast cancer; and breast carcinoma. Orthologous to human NQO2 (N-ribosyldihydronicotinamide:quinone reductase 2). [provided by Alliance of Genome Resources, Apr 2022]
Nqo2 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001163239.1 | NP_001156711.1 | ribosyldihydronicotinamide dehydrogenase [quinone] isoform 2 |
| NM_001163241.1 | NP_001156713.1 | ribosyldihydronicotinamide dehydrogenase [quinone] isoform 1 |
| NM_001163242.1 | NP_001156714.1 | ribosyldihydronicotinamide dehydrogenase [quinone] isoform 1 |
| NM_020282.3 | NP_064678.1 | ribosyldihydronicotinamide dehydrogenase [quinone] isoform 1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ribosyldihydronicotinamide dehydrogenase [quinone] |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-117393 | Bisindolylmaleimide III | Inhibitor | 98.95% | Unkown |
| HY-W843391 | Caricotamide | Activator | / | Unkown |
| HY-180168 | NQO2 activator-1 | Activator | / | Unkown |
| HY-N9765 | threo-Guaiacylglycerol β-coniferyl ether | Control | / | Unkown |
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