1. Metabolic Enzyme/Protease Immunology/Inflammation
  2. Quinone Reductase NOD-like Receptor (NLR)
  3. NQO2 activator-1

NQO2 activator-1 (Compound 1d) is a selective NQO2 activator with 20.89% increase of NQO2 activity at 10 μM. NQO2 activator-1 strongly inhibits NLRP3 inflammasome activation. NQO2 activator-1 can be used for the research of inflammation and immunology, such as rheumatoid arthritis.

For research use only. We do not sell to patients.

NQO2 activator-1

NQO2 activator-1 Chemical Structure

CAS No. : 1266401-09-5

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Description

NQO2 activator-1 (Compound 1d) is a selective NQO2 activator with 20.89% increase of NQO2 activity at 10 μM. NQO2 activator-1 strongly inhibits NLRP3 inflammasome activation. NQO2 activator-1 can be used for the research of inflammation and immunology, such as rheumatoid arthritis[1].

IC50 & Target[1]

NQO2

 

NLRP3 inflammasome

 

Molecular Weight

345.78

Formula

C18H16ClNO4

CAS No.
SMILES

ClC1=C2C(NC(/C2=C\C3=CC(OC)=C(OC)C(OC)=C3)=O)=CC=C1

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Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NQO2 activator-1
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HY-180168
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